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1

Renin inhibitory peptides. Incorporation of polar, hydrophilic end groups into an active renin inhibitory peptide template and their evaluation in a human renin-infused rat model and in conscious sodium-depleted monkeys

Thaisrivongs, Suvit, Pals, Donald T., DuCharme, Donald W., Turner, Steve R., DeGraaf, Garry L., Lawson, Judy A., Couch, Sally J., Williams, Mark V.

Journal:

Journal of Medicinal Chemistry

Year:

1991

Language:

english

File:

PDF, 1.41 MB

english, 1991

2

Structure-based discovery of tipranavir disodium (PNU-140690E): A potent, orally bioavailable, nonpeptidic HIV protease inhibitor

Suvit Thaisrivongs, Joseph W. Strohbach

Journal:

Year:

1999

Language:

english

File:

PDF, 167 KB

english, 1999

3

Katalytische Antikörper: Eine neue Klasse von Übergangszustands-Analoga zur Erzeugung hydrolytischer Antikörper

Kevan M. Shokat, Marcia K. Ko, Dr. Thomas S. Scanlan, Dr. Lynn Kochersperger, Shirlee Yonkovich, Dr. Suvit Thaisrivongs, Prof. Peter G. Schultz

Journal:

Angewandte Chemie

Year:

1990

Language:

german

File:

PDF, 753 KB

german, 1990

4

Catalytic Antibodies: A New Class of Transition-State Analogues Used to Elicit Hydrolytic Antibodies

Kevan M. Shokat, Marcia K. Ko, Dr. Thomas S. Scanlan, Dr. Lynn Kochersperger, Shirlee Yonkovich, Dr. Suvit Thaisrivongs, Prof. Peter G. Schultz

Journal:

Angewandte Chemie International Edition

Year:

1990

Language:

english

File:

PDF, 766 KB

english, 1990

5

(+)-11,11′-Di-O-methylelaiophylidene – preparation from elaiophylin and total synthesis from (R)-3-hydroxybutyrate and (S)-malate

Dieter Seebach, Hak-Fun Chow, Richard F. W. Jackson, Marius A. Sutter, Suvit Thaisrivongs, Jürg Zimmermann

Journal:

European Journal of Organic Chemistry

Year:

1986

Language:

english

File:

PDF, 1.53 MB

english, 1986

6

New 3,4-O-isopropylidene derivatives of d- and l-glucopyranosides

Jiaqiang Cai, Bruce E Davison, C Robin Ganellin, Suvit Thaisrivongs

Journal:

Tetrahedron Letters

Year:

1995

Language:

english

File:

PDF, 96 KB

english, 1995

7

The design and development of 2-aryl-2-hydroxy ethylamine substituted 1H,7H-pyrido[1,2,3-de]quinoxaline-6-carboxamides as inhibitors of human cytomegalovirus polymerase

Steven P. Tanis, Joseph W. Strohbach, Timothy T. Parker, Malcom W. Moon, Suvit Thaisrivongs, William R. Perrault, Todd A. Hopkins, Mary L. Knechtel, Nancee L. Oien, Janet L. Wieber, Kevin J. Stephansk

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 1.05 MB

english, 2010

8

Potential HIV protease inhibitors: Preparation of di-N-alkylated 2-, 6-, and 2,6-aminodeoxy-derivatives of d-glucose by direct displacement and by a novel reductive-alkylation procedure

Jiaqiang Cai, Bruce E. Davison, C.Robin Ganellin, Suvit Thaisrivongs, Keith S. Wibley

Journal:

Carbohydrate Research

Year:

1997

Language:

english

File:

PDF, 852 KB

english, 1997

9

Synthesis and pharmacological evaluation of sulfone substituted HIV protease inhibitors

Theresa M. Schwartz, Gordon L. Bundy, Joseph W. Strohbach, Suvit Thaisrivongs, Paul D. Johnson, Harvey I. Skulnick, Paul K. Tomich, Janet C. Lynn, Kong Teck Chong, Roger R. Hinshaw, Thomas J. Raub, Gu

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 184 KB

english, 1997

10

Non-peptidic HIV protease inhibitors: C2-symmetry-based design of bis-sulfonamide dihydropyrones

Musiri N. Janakiraman, Keith D. Watenpaugh, Paul K. Tomich, Kong-Teck Chong, Steve R. Turner, Ruben A. Tommasi, Suvit Thaisrivongs, Joseph W. Strohbach

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 260 KB

english, 1998

11

Crystal structure of a complex of HIV-1 protease with a dihydroxyethylene-containing inhibitor: Comparisons with molecular modeling

Narmada Thanki, J.K. Mohana Rao, Stephen I. Foundling, Alexander Wlodawer, W. Jeffrey Howe, Joseph B. Moon, John O. Hui, Alfredo G. Tomasselli, Robert L. Heinrikson, Suvit Thaisrivongs

Journal:

Protein Science

Year:

1992

Language:

english

File:

PDF, 1.11 MB

english, 1992

12

Discovery of indazoles as inhibitors of Tpl2 kinase

Yonghan Hu, Derek Cole, Rajiah Aldrin Denny, David R. Anderson, Manus Ipek, Yike Ni, Xiaolun Wang, Suvit Thaisrivongs, Timothy Chamberlain, J. Perry Hall, Julie Liu, Michael Luong, Lih-Ling Lin, Jean-

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 1.17 MB

english, 2011

13

Structure-Based Design of Novel HIV Protease Inhibitors: Sulfonamide-Containing 4-Hydroxycoumarins and 4-Hydroxy-2-pyrones as Potent Non-Peptidic Inhibitors

Thaisrivongs, Suvit, Janakiraman, Musiri N., Chong, Kong-Teck, Tomich, Paul K., Dolak, Lester A., Turner, Steve R., Strohbach, Joseph W., Lynn, Janet C., Horng, Miao-Miao, Hinshaw, Roger R.

Journal:

Journal of Medicinal Chemistry

Year:

1996

Language:

english

File:

PDF, 468 KB

english, 1996

14

Structure-Based Design of HIV Protease Inhibitors: 4-Hydroxycoumarins and 4-Hydroxy-2-pyrones as Non-peptidic Inhibitors

Thaisrivongs, Suvit, Tomich, Paul K., Watenpaugh, Keith D., Chong, Kong-Teck, Howe, W. Jeffrey, Yang, Chih-Ping, Strohbach, Joseph W., Turner, Steve R., McGrath, James P.

Journal:

Journal of Medicinal Chemistry

Year:

1994

Language:

english

File:

PDF, 2.73 MB

english, 1994

15

Structure-Based Design of Novel HIV Protease Inhibitors: Carboxamide-Containing 4-Hydroxycoumarins and 4-Hydroxy-2-pyrones as Potent Nonpeptidic Inhibitors

Thaisrivongs, Suvit, Watenpaugh, Keith D., Howe, W. Jeffrey, Tomich, Paul K., Dolak, Lester A., Chong, Kong-Teck, Tomich, Che-Shen C., Tomasselli, Alfredo G., Turner, Steve R.

Journal:

Journal of Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 4.16 MB

english, 1995

16

An approach to the total synthesis of aplysiatoxin

Ireland, Robert E., Thaisrivongs, Suvit., Dussault, Patrick H.

Journal:

Journal of the American Chemical Society

Year:

1988

Language:

english

File:

PDF, 1.86 MB

english, 1988

17

Conformationally constrained renin inhibitory peptides: .gamma.-lactam-bridged dipeptide isostere as conformational restriction

Thaisrivongs, Suvit, Pals, Donald T., Turner, Steve R., Kroll, Lisa T.

Journal:

Journal of Medicinal Chemistry

Year:

1988

Language:

english

File:

PDF, 1.10 MB

english, 1988

18

Structure-Based Design of HIV Protease Inhibitors: Sulfonamide-Containing 5,6-Dihydro-4-hydroxy-2-pyrones as Non-Peptidic Inhibitors ¶

Thaisrivongs, Suvit, Skulnick, Harvey I., Turner, Steve R., Strohbach, Joseph W., Tommasi, Ruben A., Johnson, Paul D., Aristoff, Paul A., Judge, Thomas M., Gammill, Ronald B., Morris, Jeanette K., Rom

Journal:

Journal of Medicinal Chemistry

Year:

1996

Language:

english

File:

PDF, 184 KB

english, 1996

19

Design and synthesis of potent and specific renin inhibitors containing difluorostatine, difluorostatone, and related analogs

Thaisrivongs, Suvit, Pals, Donald T., Kati, Warren M., Turner, Steve R., Thomasco, Lisa M., Watt, William

Journal:

Journal of Medicinal Chemistry

Year:

1986

Language:

english

File:

PDF, 1.00 MB

english, 1986

20

The total synthesis of ionophore antibiotics. A convergent synthesis of lasalocid A (X537A)

Ireland, Robert E., Anderson, Robert C., Badoud, Raphael, Fitzsimmons, Brian J., McGarvey, Glenn J., Thaisrivongs, Suvit, Wilcox, Craig S.

Journal:

Journal of the American Chemical Society

Year:

1983

Language:

english

File:

PDF, 2.88 MB

english, 1983

21

Inhibitors of the protease from human immunodeficiency virus: synthesis, enzyme inhibition, and antiviral activity of a series of compounds containing the dihydroxyethylene transition-state isostere

Thaisrivongs, Suvit, Turner, Steve R., Strohbach, Joseph W., TenBrink, Ruth E., Tarpley, W. Gary, McQuade, Thomas J., Heinrikson, Robert L., Tomasselli, Alfredo G., Hui, John O., Howe, W. Jeffrey

Journal:

Journal of Medicinal Chemistry

Year:

1993

Language:

english

File:

PDF, 1.97 MB

english, 1993

22

Enolate Claisen rearrangement of esters from furanoid and pyranoid glycals

Ireland, Robert E., Thaisrivongs, Suvit, Vanier, Noel, Wilcox, C. S.

Journal:

Journal of Organic Chemistry

Year:

1980

Language:

english

File:

PDF, 2.07 MB

english, 1980

23

Structure-Based Design of HIV Protease Inhibitors: 5,6-Dihydro-4-hydroxy-2-pyrones as Effective, Nonpeptidic Inhibitors

Thaisrivongs, Suvit, Romero, Donna L., Tommasi, Ruben A., Janakiraman, Musiri N., Strohbach, Joseph W., Turner, Steve R., Biles, Carolyn, Morge, Raymond R., Johnson, Paul D., Aristoff, Paul A., Tomich

Journal:

Journal of Medicinal Chemistry

Year:

1996

Language:

english

File:

PDF, 1.11 MB

english, 1996

24

.alpha.,.alpha.-Difluoro-.beta.-aminodeoxystatine-containing renin-inhibitory peptides

Thaisrivongs, Suvit, Schostarez, Heinrich J., Pals, Donald T., Turner, Steve R.

Journal:

Journal of Medicinal Chemistry

Year:

1987

Language:

english

File:

PDF, 837 KB

english, 1987

25

Aspartic Proteinases. Physiology and Pathology. By M. Fusek and V. Vetvicka. CRC Press, Inc., Boca Raton, FL. 1995. xii + 308 pp. 16 × 24 cm. ISBN 0-8493-7660-2. $179.95.

Thaisrivongs, Suvit

Journal:

Journal of Medicinal Chemistry

Year:

1996

Language:

english

File:

PDF, 71 KB

english, 1996

26

.alpha.-Methylproline-containing renin inhibitory peptides: in vivo evaluation in an anesthetized, ganglion-blocked, hog renin infused rat model

Thaisrivongs, Suvit, Pals, Donald T., Lawson, Judy A., Turner, Steve R., Harris, Douglas W.

Journal:

Journal of Medicinal Chemistry

Year:

1987

Language:

english

File:

PDF, 830 KB

english, 1987

27

Difluorostatine and difluorostatone containing peptides as potent and specific renin inhibitors

Thaisrivongs, Suvit, Pals, Donald T., Kati, Warren M., Turner, Steve R., Thomasco, Lisa M.

Journal:

Journal of Medicinal Chemistry

Year:

1985

Language:

english

File:

PDF, 363 KB

english, 1985

28

Design and synthesis of a potent and specific renin inhibitor with a prolonged duration of action in vivo

Thaisrivongs, Suvit, Pals, Donald T., Harris, Douglas W., Kati, Warren M., Turner, Steve R.

Journal:

Journal of Medicinal Chemistry

Year:

1986

Language:

english

File:

PDF, 869 KB

english, 1986

29

An efficient method for the preparation of furanoid and pyranoid glycals

Ireland, Robert E., Wilcox, Craig S., Thaisrivongs, Suvit

Journal:

Journal of Organic Chemistry

Year:

1978

Language:

english

File:

PDF, 247 KB

english, 1978

30

Diastereoselective benzyloxymercuration/demercuration of derivatives of .gamma.-alkyl-.delta.-hydroxy-.alpha.,.beta.-unsaturated esters. A new strategy for the synthesis of aldol-type products

Thaisrivongs, Suvit, Seebach, Dieter

Journal:

Journal of the American Chemical Society

Year:

1983

Language:

english

File:

PDF, 973 KB

english, 1983

31

Hydroboration of alkenes and alkynes by 1,3,2-dithiaborolane

Thaisrivongs, Suvit, Wuest, James D.

Journal:

Journal of Organic Chemistry

Year:

1977

Language:

english

File:

PDF, 720 KB

english, 1977

32

Total synthesis of (+)-11,11'-di-O-methylelaiophylidene, an aglycon of elaiophylin

Seebach, Dieter, Chow, Hak Fun, Jackson, Richard, Lawson, Kevin, Sutter, Marius, Thaisrivongs, Suvit, Zimmermann, Juerg

Journal:

Journal of the American Chemical Society

Year:

1985

Language:

english

File:

PDF, 293 KB

english, 1985

33

Inhibitors of the protease from human immunodeficiency virus: design and modeling of a compound containing a dihydroxyethylene isostere insert with high binding affinity and effective antiviral activity

Thaisrivongs, Suvit, Tomasselli, Alfredo G., Moon, Joseph B., Hui, John, McQuade, Thomas J., Turner, Steve R., Strohbach, Joseph W., Howe, W. Jeffrey, Tarpley, W. Gary, Heinrikson, Robert L.

Journal:

Journal of Medicinal Chemistry

Year:

1991

Language:

english

File:

PDF, 3.60 MB

english, 1991

34

Efficient, stereoselective total synthesis of (.+-.)-aphidicolin

Ireland, Robert E., Godfrey, Jollie D., Thaisrivongs, Suvit

Journal:

Journal of the American Chemical Society

Year:

1981

Language:

english

File:

PDF, 390 KB

english, 1981

35

Peptidomimetic HIV protease inhibitors: phosphate prodrugs with improved biological activities

Chong, Kong Teck, Ruwart, Mary J., Hinshaw, Roger R., Wilkinson, Karen F., Rush, Bob D., Yancey, Mark F., Strohbach, Joseph W., Thaisrivongs, Suvit

Journal:

Journal of Medicinal Chemistry

Year:

1993

Language:

english

File:

PDF, 376 KB

english, 1993

36

Kinetics of the inhibition of human renin by an inhibitor containing a hydroxyethylene dipeptide isostere

Kati, Warren M., Pals, Donald T., Thaisrivongs, Suvit

Journal:

Year:

1987

Language:

english

File:

PDF, 758 KB

english, 1987

37

A chiral synthesis of the left-side aldehyde for lasalocid A synthesis

Ireland, Robert E., McGarvey, Glenn J., Anderson, Robert C., Badoud, Raphael, Fitzsimmons, Brian, Thaisrivongs, Suvit

Journal:

Journal of the American Chemical Society

Year:

1980

Language:

english

File:

PDF, 364 KB

english, 1980

38

Conformationally constrained renin inhibitory peptides: cyclic (3-1)-1-(carboxymethyl)-L-prolyl-L-phenylalanyl-L-histidinamide as a conformational restriction at the P2-P4 tripeptide portion of the angiotensinogen template

Thaisrivongs, Suvit, Blinn, James R., Pals, Donald T., Turner, Steve R.

Journal:

Journal of Medicinal Chemistry

Year:

1991

Language:

english

File:

PDF, 2.30 MB

english, 1991

39

Total synthesis of (.+-.)-aphidicolin and (.+-.)-.beta.-chamigrene

Ireland, Robert E., Dow, William C., Godfrey, Jollie D., Thaisrivongs, Suvit

Journal:

Journal of Organic Chemistry

Year:

1984

Language:

english

File:

PDF, 2.39 MB

english, 1984

40

Effect of Point Mutations on the Kinetics and the Inhibition of Human Immunodeficiency Virus Type 1 Protease: Relationship to Drug Resistance

Lin, Yingzhang, Lin, Xinli, Hong, Lin, Foundling, Steve, Heinrikson, Robert L., Thaisrivongs, Suvit, Leelamanit, Wichet, Raterman, Dan, Shah, Manish

Journal:

Year:

1995

Language:

english

File:

PDF, 1.86 MB

english, 1995

41

Total synthesis of lasalocid A (X537A)

Ireland, Robert E., Thaisrivongs, Suvit, Wilcox, Craig S.

Journal:

Journal of the American Chemical Society

Year:

1980

Language:

english

File:

PDF, 395 KB

english, 1980

42

Renin inhibitory peptides. A .beta.-aspartyl residue as a replacement for the histidyl residue at the P-2 site

Thaisrivongs, Suvit, Mao, Boryeu, Pals, Donald T., Turner, Steve R., Kroll, Lisa T.

Journal:

Journal of Medicinal Chemistry

Year:

1990

Language:

english

File:

PDF, 1007 KB

english, 1990

43

Renin inhibitors. Design of angiotensinogen transition-state analogs containing novel (2R,3R,4R,5S)-5-amino-3,4-dihydroxy-2-isopropyl-7-methyloctanoic acid

Thaisrivongs, Suvit, Pals, Donald T., Kroll, Lisa T., Turner, Steve R., Han, Fu Son

Journal:

Journal of Medicinal Chemistry

Year:

1987

Language:

english

File:

PDF, 995 KB

english, 1987

44

The generation of C -glycosides through the enolate Claisen rearrangement

Ireland, Robert E., Wilcox, Craig S., Thaisrivongs, Suvit, Vanier, Noel R.

Journal:

Canadian Journal of Chemistry

Year:

1979

Language:

english

File:

PDF, 138 KB

english, 1979

45

An Inhibitor of the Protease Blocks Maturation of Human and Simian Immunodeficiency Viruses and Spread of Infection

Per Ashorn, Thomas J. McQuade, Suvit Thaisrivongs, Alfredo G. Tomasselli, W. Gary Tarpley and Bernard Moss

Journal:

Proceedings of the National Academy of Sciences

Year:

1990

Language:

english

File:

PDF, 1.22 MB

english, 1990

46

Renin inhibitory peptides: a study of structural modifications in the peptide backbone

Thaisrivongs, Suvit, Pals, Donald T., Turner, Steve R., Kroll, Lisa T.

Journal:

Journal of Hypertension

Year:

1989

File:

PDF, 232 KB

1989

47

Inhibition of the Protease of Human Immunodeficiency Virus Blocks Replication and Infectivity of the Virus in Chronically Infected Macrophages

Carlo-Federico Perno, Alberto Bergamini, Caterina D. Pesce, GiuseppeMilanese, Marcella Capozzi, Stefano Aquaro, Suvit Thaisrivongs, W. Gary Tarpley, Gerald Zon, Cartesio D'Agostini, Giovanni Rocchi, E

Journal:

The Journal of Infectious Diseases

Year:

1993

Language:

english

File:

PDF, 1.77 MB

english, 1993

48

[Annual Reports in Medicinal Chemistry] Volume 29 || Chapter 14. HIV Protease Inhibitors

Thaisrivongs, Suvit

Year:

1994

Language:

english

File:

PDF, 1.64 MB

english, 1994